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Muscular dystrophy

Cell illustration
Spring 2018

Gaining on muscle loss

Cancer, says Dan Rodgers, is a hellish parade of horribleness.

Cancerous cells multiply aggressively, interfering with the normal function of healthy organs. Tumors secrete hormones and other chemicals that exploit the body’s own defenses to the cancer’s advantage. Your body knows something is wrong, so stress hormones are released in an effort to inhibit growth processes and channel nutrients to the brain.

Deprived of resources, muscles begin to atrophy. Washington State University muscle biologist Rodgers, together with colleagues at the Baker Heart and Diabetes Institute in Australia, investigated treatments for tumor-induced muscle wasting called cancer cachexia. The research was so promising that Rodgers … » More …