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Eyes

Fall 2004

As you read this, thank your ion channels

When Mike Varnum, assistant professor, Veterinary and Comparative Anatomy, Pharmacology, and Physiology, visits the aquarium, he looks at the sea creatures a bit differently than the rest of us. What interests him most about a creature is not its bright color or odd shape, but whether it makes a toxin that blocks an ion channel. Oddly, many of the creatures do.

Many toxins, in fact, block specific ion channels, though Varnum uses different agents in his work. Ion channels are pores in the membranes of many different types of cells-highly selective, gated pores-that permit the passage of specific charged particles, or ions, into or out … » More …