Cancer

Although science has made much progress in understanding why cancer occurs—smoking, diet, environmental pollutants, viruses—the mechanisms of cancer are still elusive. Nancy Magnuson, of the School of Molecular Biosciences, has been studying an enigmatic gene called Pim-1 since 1988.

The questions I would most like to know the answers to are, “What is the normal function of the proto-oncogene called Pim-1, and how does Pim-1’s function contribute to the production of cancer?”

Although Pim-1 has long been known to be involved in cancer production, it has never been demonstrated how this occurs. Importantly, Pim-1 is only found in certain types of cells, and these are … » More …